Adorption of human fibrinogen and human serum albumin onto polyethylene

Research paper by E. Brynda, M. Houska, J. Kálal, N. A. Cepalova

Indexed on: 01 May '80Published on: 01 May '80Published in: Annals of Biomedical Engineering


The adsorption of human fibrinogen (HFb) onto polyethylene at pH 7.4 and 37°C is irreversible with the saturated value 0.51 μg/cm2. The established dependence of the concentration of irreversibly adsorbed HFb on the concentration of HFb in solution does not reflect an equilibrium between adsorption and desorption and cannot be described by an adsorption isotherm. No reversible adsorption of HFb and HSA at 37°C has been observed. At lower temperatures, both reversibly and irreversibly adsorbed HFb have been detected.