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A role of heat shock proteins for homologous recombination in Escherichia coli.

Research paper by Y Y Ogata, T T Miki, K K Sekimizu

Indexed on: 30 Nov '93Published on: 30 Nov '93Published in: Biochemical and Biophysical Research Communications



Abstract

Effects of mutations in heat shock protein genes on homologous recombination in Escherichia coli were examined by measuring intra-molecular recombinations in the plasmid, pIK43. Recombination frequencies in the groES, groEL and dnaK mutants were decreased 6 to 21% of those of the isogenic wild type strain, at a sub-lethal temperature. Thus, the heat shock proteins GroES, GroEL and DnaK apparently participate in homologous recombination in Escherichia coli.