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A divergent synthesis of modular dendrimers via sequential C-C bond fragmentation thio-Michael addition.

Research paper by Judith J Hierold, Angus A Gray-Weale, David W DW Lupton

Indexed on: 24 Aug '10Published on: 24 Aug '10Published in: Chemical Communications



Abstract

The C-C bond fragmentation of carbocycles has been developed as a new method for the divergent synthesis of dendrimers. The scope of this reaction was examined with the preparation of six first generation dendrimers from structurally diverse and readily available fragmentation precursors. By pairing the fragmentation with a thio-Michael reaction, the preparation of a [G4]-ene(24) dendrimer has been achieved.