Indexed on: 01 Sep '03Published on: 01 Sep '03Published in: Chemistry of Heterocyclic Compounds
4,4-Dialkyl-substituted N-methylmorpholinium 3,5-dicyano-6-oxo-1,4,5,6-tetrahydropyridine-2-thiolates were synthesized by the condensation of 2-alkyl-2-cyanoethyl crotonates with cyanothioacetamide and N-methylmorpholine. They were used for the production of substituted 2-alkylthio-1,4,5,6-tetrahydropyridines, 2-acetylthio-1,4,5,6,-tetrahydropyridine, 6-hydrazino-1,4,5,6-tetrahydropyridine, and 2,3,4,5,6,7-hexahydrothiazolo[3,2-a]pyridine. The structure of 6-bromo-3-bromomethyl-6,8-dicyano-7,7-dimethyl-2,3,4,5,6,7-hexahydrothiazolo[3,2-a]pyridine was proved by X-ray crystallographic analysis.
Indexed on: 01 Apr '01
Published on: 01 Apr '01 in Chemistry of Heterocyclic Compounds