2-Halogenoethyl and 2-halogenoethylthiol esters of furan series carboxylic acids

Research paper by B. V. Kurgan, A. A. Gruze, E. Ya. Lukevits, S. A. Hiller

Indexed on: 01 Jan '67Published on: 01 Jan '67Published in: Chemistry of Heterocyclic Compounds


The corresponding 2-chloroethyl (2-chloroethylthiol) esters are synthesized by the action of ethylene chlorohydrin (chloroethylmercaptan) on the acid chlorides of 5-nitrofuran carboxylic acid and 3-(5-nitrofuryl-2)acrylic acid. The acid chlorides of benzoic, furan carboxylic, and 3-(furyl-2)-acryllc acids react with ethylene sulfide, to give 2-chloroethyl esters of those acids. Ethylene oxide does not react with the acid chlorides of benzoic acid and furan series carboxylic acids either at room temperature or on heating at 50° for 1 hour.